Tkinter is easy to understand and master due to a small library. 3.
PyQt has a modern look and a good UI. ...
PyQt have a Qt Designer tool which we can use to build GUIs
than get python code of that GUI using Qt Designer.
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Python offers multiple options for developing GUI (Graphical User Interface). Out of all the GUI methods, tkinter is the most commonly used method. It is a standard Python interface to the Tk GUI toolkit shipped with Python. Python with tkinter is the fastest and easiest way to create the GUI applications.Jan 7, 2020
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I'd say tkinter is worth learning because it's the easiest way to make a simple GUI, starting from deploying it (because it comes bundled with python) and ending with actually writing the code. Simple tkinter programs aren't that hard to write.