Difference between Cat5E and Cat6 cables are that Cat6 cables, also known as Category 6 or Cat 6, offer lower crosstalk, higher signal-to-noise ratio, and are compatible for 10GBASE-T (10-Gigabit Ethernet). ... Cat6 cables provide performance speeds up to 250MHz. Cat5 cables in contrast, only provide speeds up to 100 MHz.Mar 10, 2017